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SR 59230A

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SR 59230A
IUPAC名
(2S)-1-(2-Ethylphenoxy)-3-{[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]amino}propan-2-ol
识别
CAS号 174689-39-5  checkY
PubChem 5311452
ChemSpider 4470938
SMILES
 
  • CCc1ccccc1OC[C@H](CN[C@H]2CCCc3c2cccc3)O
ChEBI 92621
IUPHAR配体 547
性质
化学式 C21H27NO2
摩尔质量 325.44 g·mol−1
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

SR 59230A是一种含氮有机化合物,化学式为C21H27NO2,能作为选择性的β受体阻滞剂[1][2][3]

参考文献

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  1. ^ Nisoli E, Tonello C, Landi M, Carruba MO. Functional studies of the first selective β3-adrenergic receptor antagonist SR 59230A in rat brown adipocytes. Mol. Pharmacol. 1996, 49 (1): 7–14. PMID 8569714. doi:10.1016/S0026-895X(25)08695-X. 
  2. ^ Bellantuono V, Cassano G, Lippe C. The adrenergic receptor subtypes present in frog (Rana esculenta) skin. Comp. Biochem. Physiol. C. August 2008, 148 (2): 160–4. PMID 18544474. doi:10.1016/j.cbpc.2008.05.001. 
  3. ^ Rickenbacher A, Seiler R, Honegger U, Shaw SG, Balsiger BM. Role of beta1-, beta2-, and beta3-adrenoceptors in contractile hypersensitivity in a model of small bowel transplantation. Surgery. January 2008, 143 (1): 94–102. PMID 18154937. doi:10.1016/j.surg.2007.06.034.