TL-1238
| TL-1238 | |
|---|---|
| |
| IUPAC名 3-[(Dimethylcarbamoyl)oxy]-N,N-diethyl-N-methylanilinium iodide | |
| 別名 | Substance 3393 |
| 識別 | |
| CAS號 | 6249-65-6 |
| PubChem | 22621 |
| ChemSpider | 21206 |
| SMILES |
|
| 性質 | |
| 化學式 | C14H23IN2O2 |
| 摩爾質量 | 378.25 g·mol−1 |
| 危險性 | |
| 主要危害 | Extremely toxic |
| 致死量或濃度： | |
LD50（中位劑量）
|
175 μg/kg (subcutaneous, mice)[1] 89 μg/kg (intravenous, mice)[1] 60 μg/kg (intravenous, mice)[2] |
| 若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。 | |
TL-1238（也稱為Substance 3393）是一種含氮有機碘化合物，分子式C
14H
23IN
2O
2，屬於氨基甲酸酯類乙醯膽鹼酯酶抑制劑[2]，結構上與新斯的明類似[3]。
參考文獻
[編輯]- ^ 1.0 1.1 Chemical Warfare Agents, and Related Chemical Problems. Parts I-II. 1958.
- ^ 2.0 2.1 Bülbring, E; Chou, TC. The relative activity of prostigmine homologues and other substances as antagonists to tubocurarine.. British Journal of Pharmacology and Chemotherapy. March 1947, 2 (1): 8–22. PMC 1509759
. PMID 19108106. doi:10.1111/j.1476-5381.1947.tb00316.x.
- ^ BLASCHKO, H; BULBRING, E; CHOU, TC. Tubocurarine antagonism and inhibition of cholinesterases.. British Journal of Pharmacology and Chemotherapy. March 1949, 4 (1): 29–32. PMC 1509899 . PMID 18113150. doi:10.1111/j.1476-5381.1949.tb00512.x.
