TL-1238
| TL-1238 | |
|---|---|
| |
| IUPAC名 3-[(Dimethylcarbamoyl)oxy]-N,N-diethyl-N-methylanilinium iodide | |
| 别名 | Substance 3393 |
| 识别 | |
| CAS号 | 6249-65-6 |
| PubChem | 22621 |
| ChemSpider | 21206 |
| SMILES |
|
| 性质 | |
| 化学式 | C14H23IN2O2 |
| 摩尔质量 | 378.25 g·mol−1 |
| 危险性 | |
| 主要危害 | Extremely toxic |
| 致死量或浓度： | |
LD50（中位剂量）
|
175 μg/kg (subcutaneous, mice)[1] 89 μg/kg (intravenous, mice)[1] 60 μg/kg (intravenous, mice)[2] |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
TL-1238（也称为Substance 3393）是一种含氮有机碘化合物，分子式C
14H
23IN
2O
2，属于氨基甲酸酯类乙酰胆碱酯酶抑制剂[2]，结构上与新斯的明类似[3]。
参考文献
[编辑]- ^ 1.0 1.1 Chemical Warfare Agents, and Related Chemical Problems. Parts I-II. 1958.
- ^ 2.0 2.1 Bülbring, E; Chou, TC. The relative activity of prostigmine homologues and other substances as antagonists to tubocurarine.. British Journal of Pharmacology and Chemotherapy. March 1947, 2 (1): 8–22. PMC 1509759
. PMID 19108106. doi:10.1111/j.1476-5381.1947.tb00316.x.
- ^ BLASCHKO, H; BULBRING, E; CHOU, TC. Tubocurarine antagonism and inhibition of cholinesterases.. British Journal of Pharmacology and Chemotherapy. March 1949, 4 (1): 29–32. PMC 1509899 . PMID 18113150. doi:10.1111/j.1476-5381.1949.tb00512.x.
