Upjohn
| The Upjohn Company | |
|---|---|
 | |
| 公司类型 | 公司  |
| 公司结局 | 与Pharmacia合并为Pharmacia & Upjohn |
| 后继机构 | Pharmacia & Upjohn 晖致（Viatris） |
| 成立 | 1886年 |
| 结束 | 1995年 |
| 总部 | 美国密歇根州波蒂奇 |
| 产业 | 制药产业 |
Upjohn是一家美国制药公司，1886年由威廉·E·厄普约翰在密歇根州黑斯廷斯成立[1]，1995年与Pharmacia合并为Pharmacia & Upjohn，现为辉瑞公司所有。
产品
[编辑]| 名称 | CAS号 | 分子式 | 化学结构 |
|---|---|---|---|
| U-47109 | 67579-13-9 | C 15H 20Cl 2N 2O |
|
| U-47700 | 82657-23-6 | C 16H 22Cl 2N 2O |
|
| 溴朵林 （U-47931E） |
67579-24-2 | C15H21BrN2O | 
|
| U-48520 | 67579-11-7 | C 16H 23ClN 2O |
|
| 依氯那明 （U-48753） |
67450-44-6 | C 16H 22Cl 2N 2O |
|
| U-48800 | 2370977-17-4 | C 17H 24Cl 2N 2O |
|
| U-49900 | 67579-76-4 | C 18H 26Cl 2N 2O |
|
| U-50211 | 98587-47-4 | C 16H 24N 2O 2 |
|
| U-50488 | 67198-13-4 | C 19H 26Cl 2N 2O |
|
| U-51574 | PubChem CID：44269303 | C 17H 24Cl 2N 2O |
|
| 螺朵林 （U-62066） |
87151-85-7 | C 22H 30Cl 2N 2O 2 |
|
| U-69593 | 96744-75-1 | C 22H 32N 2O 2 |
|
| U-77891 | 119878-31-8 | C 18H 24Br 2N 2O |
|
参考文献
[编辑]- ^ Lohrstorfer, Martha; Larson, Catherine. William E. Upjohn: Person of the Century 1853 - 1932. Kalamazoo Public Library. 2002 [December 24, 2024]. （原始内容存档于May 17, 2008）.
Known by his contemporaries as a dreamer and a tinkerer, Dr. Upjohn saw a need to improve the means of administering medicine. Most medicines of the day were in fluid form, and those in pill form were often hard and insoluble. Patients were left to try to digest the bitter medicine, with no guarantee that it would dissolve in their systems effectively. Dr. Upjohn began experimenting with making better pills in the attic of his home. Eventually he invented his "friable" pill. Friable meant that the pill could easily be crushed to a powder. The pill was patented in 1885, and its reputation quickly spread within the medical community, thanks greatly to Dr. Upjohn's marketing strategy. He sent small pine boards to thousands of physicians along with samples of his rival's hard pills, and his own friable pills. He invited doctors to hammer the pills into the boards to see which one would be the most digestible. This tactic was eventually modified, but for the next 60 years, a thumb reducing an Upjohn pill to powder was used as the trademark symbol of his company, the Upjohn Pill and Granule Company, later more widely known to the world as The Upjohn Company.