GTS-21

GTS-21
臨床資料
其他名稱	3-(2,4-dimethoxy-benzylidene)anabaseine
識別資訊
	IUPAC命名法 (3E)-3-(2,4-Dimethoxybenzylidene)-3,4,5,6-tetrahydro-2,3'-bipyridine; ;
CAS號	148372-04-7
PubChem CID	5310985;
ChemSpider	4470526;
UNII	8S399XDN2K;
CompTox Dashboard（英語：CompTox Chemicals Dashboard） (EPA)	DTXSID701027513 ;
化學資訊
化學式	C19H20N2O2
摩爾質量	308.38 g·mol−1
3D模型（JSmol（英語：JSmol））	交互式圖像;
	SMILES COc2cc(OC)ccc2C=C1CCCN=C1c3cnccc3;
	InChI InChI=1S/C19H20N2O2/c1-22-17-8-7-14(18(12-17)23-2)11-15-5-4-10-21-19(15)16-6-3-9-20-13-16/h3,6-9,11-13H,4-5,10H2,1-2H3/b15-11+; Key:RPYWXZCFYPVCNQ-RVDMUPIBSA-N;

GTS-21（或稱為3-(2,4-二甲氧基苯甲烯基)假木賊因，英語：3-(2,4-dimethoxy-benzylidene)anabaseine，縮寫DMXBA）是一種含氮有機化合物，分子式C
19H
20N
2O
2，為新煙裂鹼（假木賊因）衍生物，可用作菸鹼型乙醯膽鹼受體的部分激動劑^[1]^[2]。

參考文獻

^ Briggs CA, Anderson DJ, Brioni JD, Buccafusco JJ, Buckley MJ, Campbell JE, Decker MW, Donnelly-Roberts D, Elliott RL, Gopalakrishnan M, Holladay MW, Hui YH, Jackson WJ, Kim DJ, Marsh KC, O'Neill A, Prendergast MA, Ryther KB, Sullivan JP, Arneric SP. Functional characterization of the novel neuronal nicotinic acetylcholine receptor ligand GTS-21 in vitro and in vivo. Pharmacology, Biochemistry, and Behavior. 1997, 57 (1–2): 231–241. PMID 9164577. S2CID 205923953. doi:10.1016/S0091-3057(96)00354-1.
^ Meyer EM, Tay ET, Papke RL, Meyers C, Huang GL, de Fiebre CM. 3-[2,4-Dimethoxybenzylidene]anabaseine (DMXB) selectively activates rat alpha7 receptors and improves memory-related behaviors in a mecamylamine-sensitive manner. Brain Research. September 1997, 768 (1–2): 49–56. PMID 9369300. S2CID 13104716. doi:10.1016/S0006-8993(97)00536-2.