5α-二氫皮質酮
外觀
5α-二氫皮質酮 | |
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IUPAC名 11β,21-Dihydroxy-5α-pregnane-3,20-dione | |
系統名 (1S,3aS,3bS,5aS,9aS,9bS,10S,11aS)-10-Hydroxy-1-(hydroxyacetyl)-9a,11a-dimethylhexadecahydro-7H-cyclopenta[a]phenanthren-7-one | |
識別 | |
CAS號 | 298-25-9 |
PubChem | 3080546 |
ChemSpider | 2338305 |
SMILES |
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InChI |
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性質 | |
化學式 | C21H32O4 |
莫耳質量 | 348.47638 g/mol g·mol⁻¹ |
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。 |
5α-二氫皮質酮(英語:5α-Dihydrocorticosterone,縮寫5α-DHC,也稱為11β,21-二氫-5α-孕烷-3,20-二酮,11β,21-dihydroxy-5α-pregnane-3,20-dione)是一種天然有機化合物,化學式C21H31O4,為一種內源性的糖皮質甾體激素和神經甾體[1][2][3],由5α還原酶催化皮質酮生成[4][5][6]。
參考文獻
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- ^ Magnaghi V. GABA and neuroactive steroid interactions in glia: new roles for old players?. Curr Neuropharmacol. 2007, 5 (1): 47–64. PMC 2435342
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- ^ Abraham Weizman. Neuroactive Steroids in Brain Function, Behavior and Neuropsychiatric Disorders: Novel Strategies for Research and Treatment. Springer Science & Business Media. 1 February 2008: 48–. ISBN 978-1-4020-6854-6.
- ^ Neurosteroids and Brain Function. Academic Press. 12 December 2001: 147–. ISBN 978-0-08-054423-6.
- ^ N. Kato; M. Kawata; R.K. Pitman. PTSD: Brain Mechanisms and Clinical Implications. Springer Science & Business Media. 3 July 2007: 125–. ISBN 978-4-431-29567-9.