5α-二氢皮质酮
外观
5α-二氢皮质酮 | |
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IUPAC名 11β,21-Dihydroxy-5α-pregnane-3,20-dione | |
系统名 (1S,3aS,3bS,5aS,9aS,9bS,10S,11aS)-10-Hydroxy-1-(hydroxyacetyl)-9a,11a-dimethylhexadecahydro-7H-cyclopenta[a]phenanthren-7-one | |
识别 | |
CAS号 | 298-25-9 |
PubChem | 3080546 |
ChemSpider | 2338305 |
SMILES |
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InChI |
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性质 | |
化学式 | C21H32O4 |
摩尔质量 | 348.47638 g/mol g·mol⁻¹ |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
5α-二氢皮质酮(英語:5α-Dihydrocorticosterone,缩写5α-DHC,也称为11β,21-二氢-5α-孕烷-3,20-二酮,11β,21-dihydroxy-5α-pregnane-3,20-dione)是一种天然有机化合物,化学式C21H31O4,为一种内源性的糖皮质甾体激素和神经甾体[1][2][3],由5α還原酶催化皮质酮生成[4][5][6]。
参考文献
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- ^ Magnaghi V. GABA and neuroactive steroid interactions in glia: new roles for old players?. Curr Neuropharmacol. 2007, 5 (1): 47–64. PMC 2435342
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- ^ Abraham Weizman. Neuroactive Steroids in Brain Function, Behavior and Neuropsychiatric Disorders: Novel Strategies for Research and Treatment. Springer Science & Business Media. 1 February 2008: 48–. ISBN 978-1-4020-6854-6.
- ^ Neurosteroids and Brain Function. Academic Press. 12 December 2001: 147–. ISBN 978-0-08-054423-6.
- ^ N. Kato; M. Kawata; R.K. Pitman. PTSD: Brain Mechanisms and Clinical Implications. Springer Science & Business Media. 3 July 2007: 125–. ISBN 978-4-431-29567-9.