三级淋巴结构

三级淋巴结构（英语：tertiary lymphoid structure，TLS）也称为“第三淋巴样器官”（tertiary lymphoid organs，TLO）或“异位淋巴样结构”（ectopic lymphatic tissues）是非生理条件下非淋巴组织中后天产生的有组织的免疫细胞聚集体，通常与肿瘤免疫、慢性病和自体免疫有关^[1]^[2]。

参考文献

^ Pipi, E; Nayar, S; Gardner, DH; Colafrancesco, S; Smith, C; Barone, F. Tertiary Lymphoid Structures: Autoimmunity Goes Local.. Frontiers in immunology. 2018, 9: 1952. PMID 30258435. doi:10.3389/fimmu.2018.01952.
^ Tang, Z; Bai, Y; Fang, Q; Yuan, Y; Zeng, Q; Chen, S; Xu, T; Chen, J; Tan, L; Wang, C; Li, Q; Lin, J; Yang, Z; Wu, X; Shi, G; Wang, J; Yin, C; Guo, J; Liu, S; Peng, S; Kuang, M. Spatial transcriptomics reveals tryptophan metabolism restricting maturation of intratumoral tertiary lymphoid structures.. Cancer cell. 2025-04-01. PMID 40185093 请检查|pmid=值 (帮助). doi:10.1016/j.ccell.2025.03.011.

[1] Pipi, E; Nayar, S; Gardner, DH; Colafrancesco, S; Smith, C; Barone, F. Tertiary Lymphoid Structures: Autoimmunity Goes Local.. Frontiers in immunology. 2018, 9: 1952. PMID 30258435. doi:10.3389/fimmu.2018.01952.

[2] Tang, Z; Bai, Y; Fang, Q; Yuan, Y; Zeng, Q; Chen, S; Xu, T; Chen, J; Tan, L; Wang, C; Li, Q; Lin, J; Yang, Z; Wu, X; Shi, G; Wang, J; Yin, C; Guo, J; Liu, S; Peng, S; Kuang, M. Spatial transcriptomics reveals tryptophan metabolism restricting maturation of intratumoral tertiary lymphoid structures.. Cancer cell. 2025-04-01. PMID 40185093 请检查|pmid=值 (帮助). doi:10.1016/j.ccell.2025.03.011.

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