TAX1BP3

TAX1BP3
已知的結構
PDB	直系同源搜索: PDBe RCSB
PDBID列表
	2KG2、2L4S、2L4T、2VZ5、3GJ9、3SFJ、4E3B、4NNL、4NNM
識別號
别名	TAX1BP3；, TIP-1, TIP1, Tax1 binding protein 3
外部ID	OMIM：616484 MGI：1923531 HomoloGene：8749 GeneCards：TAX1BP3
基因位置（人类）
染色体	17號染色體
终止	3,668,679 bp
基因位置（小鼠）
染色体	小鼠11号染色体
终止	73,073,988 bp
基因本體
分子功能	• beta-catenin binding; • protein C-terminus binding; • 血浆蛋白结合;
細胞組分	• 細胞質; • 细胞质基质; • 细胞膜; • 外排體; • 膜; • 细胞核; • fibrillar center; • actin cytoskeleton; • 細胞內膜結合細胞器;
生物學過程	• negative regulation of Wnt signaling pathway; • negative regulation of protein localization to cell surface; • regulation of Wnt signaling pathway; • Wnt信号通路; • Rho protein signal transduction; • activation of GTPase activity; • negative regulation of cell population proliferation;
	Sources:Amigo / QuickGO
直系同源
	30851
	76281
	ENSG00000213977
	ENSMUSG00000040158
	O14907
	Q9DBG9
	NM_014604; NM_001204698
	NM_029564
	NP_001191627; NP_055419
	NP_083840
	維基數據
檢視/編輯人類	檢視/編輯小鼠

TAX1BP3（Tax1 binding protein 3，“Tax1结合蛋白3”）是人类基因 TAX1BP3 编码的蛋白质^[5]^[6]^[7]，其名称来源于能通过带有的PDZ结构域和人類嗜T淋巴球病毒一型（HTLV-1）的蛋白Tax1结合^[7]。

参考文献

^ ^1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000213977 - Ensembl, May 2017
^ ^2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000040158 - Ensembl, May 2017
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA. A "double adaptor" method for improved shotgun library construction. Anal Biochem. Jun 1996, 236 (1): 107–113. PMID 8619474. doi:10.1006/abio.1996.0138.
^ Touchman JW, Anikster Y, Dietrich NL, Maduro VV, McDowell G, Shotelersuk V, Bouffard GG, Beckstrom-Sternberg SM, Gahl WA, Green ED. The genomic region encompassing the nephropathic cystinosis gene (CTNS): complete sequencing of a 200-kb segment and discovery of a novel gene within the common cystinosis-causing deletion. Genome Res. Mar 2000, 10 (2): 165–173. PMC 310836 . PMID 10673275. doi:10.1101/gr.10.2.165.
^ ^7.0 ^7.1 Entrez Gene: TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3.