PDZ结构域
 | |||||||||||
| 鑑定 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 標誌 | PDZ | ||||||||||
| Pfam | PF00595（旧版） | ||||||||||
| InterPro | IPR001478 | ||||||||||
| SMART | PDZ | ||||||||||
| PROSITE | PDOC50106 | ||||||||||
| SCOP | 1lcy / SUPFAM | ||||||||||
| CDD | cd00136 | ||||||||||
| |||||||||||
PDZ结构域（英語：PDZ domain）是一个长约80-90个氨基酸残基的蛋白质结构域，广泛存在于细菌、真菌、植物、病毒[1]、以及动物[2]的信号转导相关蛋白中。
参考文献
[编辑]- ^ Boxus M, Twizere JC, Legros S, Dewulf JF, Kettmann R, Willems L. The HTLV-1 Tax interactome. Retrovirology. August 2008, 5: 76. PMC 2533353
. PMID 18702816. doi:10.1186/1742-4690-5-76 .
- ^ Ponting CP. Evidence for PDZ domains in bacteria, yeast, and plants. Protein Science. February 1997, 6 (2): 464–8. PMC 2143646 . PMID 9041651. doi:10.1002/pro.5560060225.
外部链接
[编辑]- Eukaryotic Linear Motif resource motif class LIG_PDZ_Class_1
- Eukaryotic Linear Motif resource motif class LIG_PDZ_Class_2
- Eukaryotic Linear Motif resource motif class LIG_PDZ_Class_3
- The PDZ Domain as a Complex Adaptive System A concise technical summary and a statement of principal findings and ramifications of the PDZ Domain as a Complex Adaptive System
- NCBI conserved domains entry
- https://www.pdznet.eu - An EU project to advance our understanding of the cellular signaling pathways and therapeutic potential of proteins comprising PDZ domains in healthy and pathological conditions such as cancer and neurological diseases.