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利非他明

维基百科,自由的百科全书
利非他明
臨床資料
ATC碼
  • 未分配
法律規範狀態
法律規範
识别信息
  • (R)-N,N-dimethyl-1,2-diphenyl-ethanamine
CAS号7262-75-1  checkY
PubChem CID
ChemSpider
UNII
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C16H19N
摩尔质量225.34 g·mol−1

利非他明INN:lefetamine)是一种兼具兴奋剂类阿片镇痛剂功效的精神活性药物,其弱效镇痛作用与可待因相当[1][2][3]。它在20世纪40年代间被发明,20世纪50年代后在日本被大规模使用[4][5]

参考文献

[编辑]
  1. ^ Dodds EC, Lawson W, Simpson SA, Williams PC. Testing diphenylethylamine compounds for analgesic action. The Journal of Physiology. June 1945, 104 (1): 47–51. PMC 1393527可免费查阅. PMID 16991666. doi:10.1113/jphysiol.1945.sp004105. 
  2. ^ Fujimura H, Kawai K. Pharmacological Studies on Diphenylalkylamine Derivatives. (I) (PDF). Bulletin of the Institute for Chemical Research, Kyoto University. 1961, 39 (1): 67–77 [2011-09-25]. (原始内容存档 (PDF)于2012-05-01). 
  3. ^ Fujimura H, Kawai K, Ohata K, Shibata S. Pharmacological Studies on Diphenylalkylamine Derivatives. (II): On the Actions of l-1,2-Diphenyl-1-dimethylaminoethane Hydrochloride (SPA) (PDF). Bulletin of the Institute for Chemical Research, Kyoto University. 1961, 39 (1): 78–94 [2012-06-30]. (原始内容存档 (PDF)于2016-03-04). 
  4. ^ K. Ogiu et al., J. Pharm. Soc. Japan 80, 283 (1960)
  5. ^ Mannelli P, Janiri L, De Marinis M, Tempesta E. Lefetamine: new abuse of an old drug--clinical evaluation of opioid activity. Drug and Alcohol Dependence. 1989 Oct;24(2):95-101.