ADB-FUBHQUCA

ADB-FUBHQUCA
識別資訊
	IUPAC命名法 (S)-N-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1,4-dihydroquinoline-3-carboxamide; ;
PubChem CID	165361603;
CompTox Dashboard（英語：CompTox Chemicals Dashboard） (EPA)	DTXSID201342574 ;
化學資訊
化學式	C23H26FN3O2
摩爾質量	395.48 g·mol−1
3D模型（JSmol（英語：JSmol））	交互式圖像;
	SMILES NC(=O)[C@@H](NC(=O)C=1Cc2ccccc2N(C=1)Cc1ccc(F)cc1)C(C)(C)C;
	InChI InChI=1S/C23H26FN3O2/c1-23(2,3)20(21(25)28)26-22(29)17-12-16-6-4-5-7-19(16)27(14-17)13-15-8-10-18(24)11-9-15/h4-11,14,20H,12-13H2,1-3H3,(H2,25,28)(H,26,29); Key:WEFDGWANUSMUJL-UHFFFAOYSA-N;

ADB-FUBHQUCA是一種含氮有機氟化合物，分子式C
23H
26FN
3O
2，能作為大麻素受體的激動劑^[1]，結構上與ADB-FUBICA類似，不過吲哚基團替換為了1,4-二氫喹啉基團^[2]^[3]。

參考文獻

^ New Substance Report. 118. ADB-FUBHQUCA. AIPSIN monitoring. 18 February 2022 （俄語）.
^ Pasquini S, De Rosa M, Pedani V, Mugnaini C, Guida F, Luongo L, et al. Investigations on the 4-quinolone-3-carboxylic acid motif. 4. Identification of new potent and selective ligands for the cannabinoid type 2 receptor with diverse substitution patterns and antihyperalgesic effects in mice. Journal of Medicinal Chemistry. August 2011, 54 (15): 5444–5453. PMID 21702498. doi:10.1021/jm200476p.
^ Pasquini S, De Rosa M, Ligresti A, Mugnaini C, Brizzi A, Caradonna NP, et al. Investigations on the 4-quinolone-3-carboxylic acid motif. 6. Synthesis and pharmacological evaluation of 7-substituted quinolone-3-carboxamide derivatives as high affinity ligands for cannabinoid receptors. European Journal of Medicinal Chemistry. December 2012, 58: 30–43. PMID 23085772. doi:10.1016/j.ejmech.2012.09.035.