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P-7521

维基百科,自由的百科全书
P-7521
识别信息
  • 3-[9-methoxy-3-(2-phenylethyl)-3-azabicyclo[3.3.1]nonan-9-yl]phenol
CAS号92836-37-8
PubChem CID
ChemSpider
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C23H29NO2
摩尔质量351.49 g·mol−1
3D模型(JSmol英语JSmol
  • COC1(C2CCCC1CN(C2)CCC3=CC=CC=C3)C4=CC(=CC=C4)O
  • InChI=1S/C23H29NO2/c1-26-23(19-9-6-12-22(25)15-19)20-10-5-11-21(23)17-24(16-20)14-13-18-7-3-2-4-8-18/h2-4,6-9,12,15,20-21,25H,5,10-11,13-14,16-17H2,1H3
  • Key:UXFOUDJIDGKJDT-UHFFFAOYSA-N

P-7521是一种含氮有机化合物,化学式C
23
H
29
NO
2
,1980年代在中国研发,能作为阿片类止痛药[1][2][3][4]

另见

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参考文献

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  1. ^ Zhou J, Zheng WJ, Chi ZQ. [Analgesic activity and respiratory inhibition of 3-beta-phenylethyl)-9 beta-methoxy-9 alpha-(m-hydroxyphenyl)-3-azabicyclo [3,3,1]-nonane (P-7521) in rabbits]. Zhongguo Yao Li Xue Bao = Acta Pharmacologica Sinica. January 1987, 8 (1): 10–13. PMID 2955652. 
  2. ^ Zhou DH, Ge BL, Xu XJ, Chi ZQ. [Effects of the long-acting analgesics 3-(beta-phenylethyl)-9 beta-methoxy-9 alpha-(m-hydroxyphenyl)-3-azabicycles [3,3,1]-nonane (P-7521) on opiate receptor binding in vitro]. Zhongguo Yao Li Xue Bao = Acta Pharmacologica Sinica. November 1988, 9 (6): 511–515. PMID 2855686. 
  3. ^ Jin WQ, Fan LQ, Chen XJ, Chi ZQ. P-7521--a new irreversible opioid ligand. Zhongguo Yao Li Xue Bao = Acta Pharmacologica Sinica. May 1989, 10 (3): 205–210. PMID 2558497. 
  4. ^ Chi ZQ, Jin WQ. A potent and long-lasting ligand, azabicyclononane (P-7521). Progress in Clinical and Biological Research. 1990, 328: 1–4. PMID 2154758.