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O-823

维基百科,自由的百科全书
O-823
识别信息
  • 7-[(6aR,10aR)-1-hydroxy-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-3-yl]hept-5-ynenitrile
CAS号184433-64-5  checkY
PubChem CID
ChemSpider
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C23H27NO2
摩尔质量349.47 g·mol−1
3D模型(JSmol英语JSmol
  • Oc2cc(CC#CCCCC#N)cc(OC1(C)C)c2C3C1CC=C(C)C3
  • InChI=1S/C23H27NO2/c1-16-10-11-19-18(13-16)22-20(25)14-17(9-7-5-4-6-8-12-24)15-21(22)26-23(19,2)3/h10,14-15,18-19,25H,4,6,8-9,11,13H2,1-3H3/t18-,19-/m1/s1 checkY
  • Key:MZMMIGOIGWVGEH-RTBURBONSA-N checkY

O-823是一种含氮有机化合物,化学式C
26
H
39
NO
3
,属于一种大麻素,由美国Organix Inc公司开发,是大麻素受体CB1部分激动剂[1][2][3]

参考文献

[编辑]
  1. ^ Pertwee RG, Fernando SR, Griffin G, Ryan W, Razdan RK, Compton DR, Martin BR. Agonist-antagonist characterization of 6'-cyanohex-2'-yne-delta 8-tetrahydrocannabinol in two isolated tissue preparations. European Journal of Pharmacology. November 1996, 315 (2): 195–201. PMID 8960884. doi:10.1016/s0014-2999(96)00631-0. 
  2. ^ Griffin G, Wray EJ, Rorrer WK, Crocker PJ, Ryan WJ, Saha B, et al. An investigation into the structural determinants of cannabinoid receptor ligand efficacy. British Journal of Pharmacology. April 1999, 126 (7): 1575–84. PMC 1565939可免费查阅. PMID 10323589. doi:10.1038/sj.bjp.0702469. 
  3. ^ Griffin G, Wray EJ, Martin BR, Abood ME. Cannabinoid agonists and antagonists discriminated by receptor binding in rat cerebellum. British Journal of Pharmacology. October 1999, 128 (3): 684–8. PMC 1571656可免费查阅. PMID 10516649. doi:10.1038/sj.bjp.0702806.