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O-1602

维基百科,自由的百科全书
O-1602
识别信息
  • 5-methyl-4-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]benzene-1,3-diol
CAS号317321-41-8
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C17H22O2
摩尔质量258.36 g·mol−1
3D模型(JSmol英语JSmol
  • CC1=C[C@@H](C2=C(C)C=C(O)C=C2O)[C@H](C(C)=C)CC1
  • InChI=1S/C17H22O2/c1-10(2)14-6-5-11(3)7-15(14)17-12(4)8-13(18)9-16(17)19/h7-9,14-15,18-19H,1,5-6H2,2-4H3/t14-,15+/m0/s1
  • Key:KDZOUSULXZNDJH-LSDHHAIUSA-N

O-1602是一种含氮有机化合物,化学式C
17
H
22
O
2
,属于一种大麻素,由美国Organix Inc公司开发,化学结构上与异常大麻二酚(Abn-CBD)相似,而和经典的大麻素受体CB1和CB2无明显的成键倾向[1][2][3]

参考文献

[编辑]
  1. ^ Ashton JC. The atypical cannabinoid O-1602: targets, actions, and the central nervous system. Central Nervous System Agents in Medicinal Chemistry. September 2012, 12 (3): 233–9. PMID 22831390. doi:10.2174/187152412802430156. 
  2. ^ Schuelert N, McDougall JJ. The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55. Neuroscience Letters. August 2011, 500 (1): 72–6. PMID 21683763. S2CID 3410391. doi:10.1016/j.neulet.2011.06.004. 
  3. ^ Schicho R, Bashashati M, Bawa M, et al. The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment. Inflammatory Bowel Diseases. August 2011, 17 (8): 1651–64. PMC 3116968可免费查阅. PMID 21744421. doi:10.1002/ibd.21538.