N-苄基-3-乙酰基吲哚
| N-苄基-3-乙酰基吲哚 | |
|---|---|
| 别名 | 1-(1-苄基-1H-吲哚-3-基)乙酮 |
| 识别 | |
| CAS号 | 93315-38-9 
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| SMILES |
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| 性质 | |
| 化学式 | C17H15NO |
| 摩尔质量 | 249.31 g·mol−1 |
| 熔点 | 97-99 °C[1] 109-110 °C[2] |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
N-苄基-3-乙酰基吲哚是一种含氮杂环化合物，化学式为C17H15NO。它可由3-乙酰基吲哚、氢化钠和苄溴反应制得。[1]
它可以被硼氢化钠还原为α-甲基-N-苄基吲哚-3-甲醇。[3]
参考文献
[编辑]- ^ 1.0 1.1 Barreca, Maria Letizia; Ferro, Stefania; Rao, Angela; De Luca, Laura; Zappala, Maria; Monforte, Anna-Maria; Debyser, Zeger; Witvrouw, Myriam; Chimirri, Alba. Pharmacophore-Based Design of HIV-1 Integrase Strand-Transfer Inhibitors. J. Med. Chem. 2005, 48, 22, 7084–7088. doi:10.1021/jm050549e.
- ^ Venkatanarayana, M.; Dubey, Pramod K. Novel and simple methodology for the synthesis of 3-acetylindoles and their N-alkyl derivatives using TBAB as phase transfer catalyst. J. Med. Chem. 2004, 47, 21, 5298–5310. doi:10.2174/157017811799304395.
- ^ Santoso, Mardi; et al. Some acid-catalyzed reactions of indol-3-yl and indol-2-yl disubstituted methanols. Collection of Czechoslovak Chemical Communications (2009), 74 (7-8), 1137-1150. doi:10.1135/cccc2009023.