MY-5445
| MY-5445 | |
|---|---|
| |
| IUPAC名 N-(3-Chlorophenyl)-4-phenylphthalazin-1-amine | |
| 识别 | |
| CAS号 | 78351-75-4 
|
| PubChem | 1348 |
| ChemSpider | 1308 |
| SMILES |
|
| InChI |
|
| InChIKey | CEHQLKSLMFIHBF-UHFFFAOYAQ |
| EINECS | 636-069-4 |
| 性质 | |
| 化学式 | C20H14ClN3 |
| 摩尔质量 | 331.8 g·mol−1 |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
MY-5445是一种含氮有机氯化合物，分子式C
20H
14ClN
3，可作为第五型磷酸二酯酶抑制劑（PDE5抑制剂）[1][2]。
参考文献
[编辑]- ^ Nagendran, J; Archer, SL; Soliman, D; Gurtu, V; Moudgil, R; Haromy, A; St. Aubin, C; Webster, L; Rebeyka, IM; Ross, DB; Light, PE; Dyck, JR; Michelakis, ED. Phosphodiesterase Type 5 is Highly Expressed in the Hypertrophied Human Right Ventricle, and Acute Inhibition of Phosphodiesterase Type 5 Improves Contractility (PDF). Circulation. 17 July 2007, 116 (3): 238–48. PMID 17606845. S2CID 7612061. doi:10.1161/circulationaha.106.655266
.
- ^ Hagiwara, M; Endo, T; Kanayama, T; Hidaka, H. Effect of 1-(3-Chloroanilino)-4-phenylphthalazine (MY-5445), a Specific Inhibitor of Cyclic GMP Phosphodiesterase, on Human Platelet Aggregation. The Journal of Pharmacology and Experimental Therapeutics. February 1984, 228 (2): 467–71. PMID 6141286.
