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JWH-019

维基百科,自由的百科全书
JWH-019
法律規範狀態
法律規範
识别信息
  • 1-Hexyl-3-(naphthalen-1-oyl)indole
CAS号209414-08-4  checkY
ChemSpider
UNII
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C25H25NO
摩尔质量355.48 g·mol−1
3D模型(JSmol英语JSmol
  • c3cccc2c3cccc2C(=O)c1cn(CCCCCC)c4c1cccc4
  • InChI=1S/C25H25NO/c1-2-3-4-9-17-26-18-23(21-14-7-8-16-24(21)26)25(27)22-15-10-12-19-11-5-6-13-20(19)22/h5-8,10-16,18H,2-4,9,17H2,1H3
  • Key:PALJPGHWDUHUPO-UHFFFAOYSA-N

JWH-019,化学名1-己基-3-(1-萘甲酰基)吲哚(英語:1-hexyl-3-(1-naphthoyl)indole),分子式C
25
H
25
NO
,属于萘甲酰基吲哚JWH系列大麻素,可作为镇痛药[2][3][4]

参考文献

[编辑]
  1. ^ Ustawa z dnia 15 kwietnia 2011 r. o zmianie ustawy o przeciwdziałaniu narkomanii ( Dz.U. 2011 nr 105 poz. 614 ). Internetowy System Aktów Prawnych. [12 June 2011]. 
  2. ^ Aung MM, Griffin G, Huffman JW, Wu M, Keel C, Yang B, et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB(1) and CB(2) receptor binding. Drug and Alcohol Dependence. August 2000, 60 (2): 133–40. PMID 10940540. doi:10.1016/S0376-8716(99)00152-0. 
  3. ^ Poso A, Huffman JW. Targeting the cannabinoid CB2 receptor: modelling and structural determinants of CB2 selective ligands. British Journal of Pharmacology. January 2008, 153 (2): 335–46. PMC 2219524可免费查阅. PMID 17982473. doi:10.1038/sj.bjp.0707567. 
  4. ^ Ashton JC, Wright JL, McPartland JM, Tyndall JD. Cannabinoid CB1 and CB2 receptor ligand specificity and the development of CB2-selective agonists. Current Medicinal Chemistry. 2008, 15 (14): 1428–43. PMID 18537620. doi:10.2174/092986708784567716.