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ADB-FUBIATA

维基百科,自由的百科全书
ADB-FUBIATA
识别信息
  • (2S)-2-[[2-[1-[(4-fluorophenyl)methyl]indol-3-yl]acetyl]amino]-3,3-dimethylbutanamide
CAS号2938025-73-9  ☒N
PubChem CID
ChemSpider
UNII
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C23H26FN3O2
摩尔质量395.48 g·mol−1
3D模型(JSmol英语JSmol
  • CC(C)(C)[C@@H](C(=O)N)NC(=O)CC1=CN(C2=CC=CC=C21)CC3=CC=C(C=C3)F
  • InChI=1S/C23H26FN3O2/c1-23(2,3)21(22(25)29)26-20(28)12-16-14-27(19-7-5-4-6-18(16)19)13-15-8-10-17(24)11-9-15/h4-11,14,21H,12-13H2,1-3H3,(H2,25,29)(H,26,28)/t21-/m1/s1
  • Key:KHAUCCNSUMBFOT-OAQYLSRUSA-N

ADB-FUBIATA是一种含氮有机氟化合物,分子式C
23
H
26
FN
3
O
2
,能作为大麻素受体激动剂[2],其对CB1的EC50仅为635 nM,对CB2几乎无活性[3][4]

参考文献

[编辑]
  1. ^ Anvisa. RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial [Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control]. Diário Oficial da União. 2023-07-24 (2023-07-25) [2023-08-27]. (原始内容存档于2023-08-27) (巴西葡萄牙语). 
  2. ^ 关于将合成大麻素类物质和氟胺酮等18种物质列入《非药用类麻醉药品和精神药品管制品种增补目录》的公告 [Announcement on the inclusion of 18 substances including synthetic cannabinoids and fluamine in the "Additional Catalogue of Controlled Varieties of Non-medicinal Narcotics and Psychotropic Drugs"]. Ministry of Public Security of the People's Republic of China. 12 May 2021 (Chinese). 
  3. ^ Deventer MH, Van Uytfanghe K, Vinckier IM, Reniero F, Guillou C, Stove CP. A new cannabinoid receptor 1 selective agonist evading the 2021 "China ban": ADB-FUBIATA. Drug Testing and Analysis. September 2022, 14 (9): 1639–1644. PMID 35570246. S2CID 248812121. doi:10.1002/dta.3285. hdl:1854/LU-01GQ757043ZZ4MNSKMZ52FAKJ1可免费查阅. 
  4. ^ Pasin D, Nedahl M, Mollerup CB, Tortzen C, Reitzel LA, Dalsgaard PW. Identification of the synthetic cannabinoid-type new psychoactive substance, CH-PIACA, in seized material. Drug Testing and Analysis. September 2022, 14 (9): 1645–1651. PMC 9544820可免费查阅. PMID 35687099. doi:10.1002/dta.3333.