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2,3'-联苯酚

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2,3'-联苯酚
识别
CAS号 31835-45-7  checkY
SMILES
 
  • OC1=CC=CC(=C1)C=2C=CC=CC2O
性质
化学式 C12H10O2
摩尔质量 186.21 g·mol−1
熔点 92-93 °C[1]
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

2,3'-联苯酚是一种有机化合物,化学式为C12H10O2。它可由3-碘苯酚和2-羟基苯硼酸,或2-碘苯酚和3-羟基苯硼酸在碳酸钾存在下、催化下反应制得。[2]它和烯丙基溴碳酸钾丙酮中回流,可以得到2,3'-二(烯丙氧基)联苯。[3]

参考文献

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  1. ^ María Sánchez-Peris; et al. Synthesis and evaluation of biphenyl derivatives as potential downregulators of VEGF protein secretion and telomerase-related gene expressions. Bioorganic & Medicinal Chemistry, 2016. 24 (14). 3108-3115. doi:10.1016/j.bmc.2016.05.030.
  2. ^ Bernd Schmidt; Martin Riemer. Suzuki–Miyaura Coupling of Halophenols and Phenol Boronic Acids: Systematic Investigation of Positional Isomer Effects and Conclusions for the Synthesis of Phytoalexins from Pyrinae. J. Org. Chem. 2014, 79, 9, 4104–4118. doi:10.1021/jo500675a.
  3. ^ María Sánchez-Peris; et al. Synthesis of honokiol analogues and evaluation of their modulating action on VEGF protein secretion and telomerase-related gene expressions. Chemical Biology & Drug Design (2017), 89 (4), 577-584. doi:10.1111/cbdd.12880.