阿尼地坦

阿尼地坦
臨床資料
ATC碼	未分配;
识别信息
	IUPAC命名法 N-[(2R)-3,4-dihydro-2H-chromen-2-ylmethyl]-N'-(1,4,5,6-tetrahydropyrimidin-2-yl)propane-1,3-diamine; ;
CAS号	152317-89-0 ; 155428-00-5
PubChem CID	66004;
IUPHAR/BPS	120;
ChemSpider	59396 ;
UNII	B57Z82EOGE; Dihydrochloride: 54PE58MGKB ;
KEGG	D02826 ;
ChEMBL	ChEMBL88240 ;
化学信息
化学式	C17H26N4O
摩尔质量	302.42 g·mol−1
3D模型（JSmol（英语：JSmol））	交互式图像;
	SMILES C1CNC(=NC1)NCCCNCC2CCC3=CC=CC=C3O2;
	InChI InChI=1S/C17H26N4O/c1-2-6-16-14(5-1)7-8-15(22-16)13-18-9-3-10-19-17-20-11-4-12-21-17/h1-2,5-6,15,18H,3-4,7-13H2,(H2,19,20,21)/t15-/m1/s1 ; Key:QVSXOXCYXPQXMF-OAHLLOKOSA-N ;

阿尼地坦（英語：Alniditan）是一种含氮有机化合物，化学式C
17H
26N
4O，有5-HT_1D受体激动剂效应，可用作偏頭痛药物^[1]。

参考文献

^ Leysen JE, Gommeren W, Heylen L, Luyten WH, Van de Weyer I, Vanhoenacker P, et al. Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamine and [3H]alniditan. Molecular Pharmacology. December 1996, 50 (6): 1567–1580. PMID 8967979. doi:10.1016/S0026-895X(25)09616-6.
^ Van Lommen G, De Bruyn M, Schroven M, Verschueren W, Janssens W, Verrelst J, Leysen J. The discovery of a series of new non-indole 5HT1D agonists. Bioorganic & Medicinal Chemistry Letters. 1995, 5 (22): 2649–2654. doi:10.1016/0960-894X(95)00473-7.