志賀毒素
外观
(重定向自志賀樣毒素)

志賀样毒素alpha亚基 | |
---|---|
鑑定 | |
標誌 | SLT_alpha |
InterPro | IPR016331 |
SCOP | 1r4q / SUPFAM |
志賀样毒素beta亚基 | |||||||||
---|---|---|---|---|---|---|---|---|---|
鑑定 | |||||||||
標誌 | SLT_beta | ||||||||
Pfam | PF02258(旧版) | ||||||||
InterPro | IPR003189 | ||||||||
SCOP | 2bos / SUPFAM | ||||||||
TCDB | 1.C.54 | ||||||||
|
志賀毒素(英語:Shiga toxin,簡寫為STX)是由志賀氏菌屬等细菌所分泌的外毒素,由α和β亚基組合而成,位于细菌基因组的原噬菌体段[1],这一蛋白最早由志賀潔发现[2]。过去常把大腸桿菌分泌的志賀毒素称为志賀样毒素(Shiga-like toxin,SLT),但现在这一词已不常用,能产生志賀毒素的大腸桿菌有O157:H7型和O104:H4型等[3][4][5]。
参考文献
[编辑]- ^ Friedman D; Court D. Bacteriophage lambda: alive and well and still doing its thing. Current Opinion in Microbiology. 2001, 4 (2): 201–7. PMID 11282477. doi:10.1016/S1369-5274(00)00189-2.
- ^ Trofa, Andrew F.; Ueno-Olsen, Hannah; Oiwa, Ruiko; Yoshikawa, Masanosuke. Dr. Kiyoshi Shiga: Discoverer of the Dysentery Bacillus. Clinical Infectious Diseases. 1999-11-01, 29 (5): 1303–1306. ISSN 1058-4838. PMID 10524979. doi:10.1086/313437
(英语).
- ^ Zhu Q; Li L; Guo Z; Yang R. Identification of Shiga-like toxin Escherichia coli isolated from children with diarrhea by polymerase chain reaction. Chin. Med. J. June 2002, 115 (6): 815–8. PMID 12123543.
- ^ Beutin L. Emerging enterohaemorrhagic Escherichia coli, causes and effects of the rise of a human pathogen. Journal of Veterinary Medicine. B, Infectious Diseases and Veterinary Public Health. 2006, 53 (7): 299–305. PMID 16930272. doi:10.1111/j.1439-0450.2006.00968.x.
- ^ Spears; et al. A comparison of Enteropathogenic and enterohaemorragic E.coli pathogenesis. FEMS Microbiology Letters. 2006, 255 (2): 187–202. PMID 16448495. doi:10.1111/j.1574-6968.2006.00119.x
.