1-(2-噻吩基)-2-丙胺

1-(2-噻吩基)-2-丙胺
臨床資料
其他名稱	Thiophenylpropylamine; 1-Methyl-2-thiophen-2-yl-ethylamine; 2-(2-Aminopropyl)thiophene; 1-(2-Thienyl)-2-aminopropane
法律規範狀態
法律規範	加：Schedule I; 中：非药用类麻醉药品和精神药品; 德：Anlage I;
识别信息
	IUPAC命名法 1-(thiophen-2-yl)-2-aminopropane; ;
CAS号	30433-93-3
PubChem CID	6484133;
ChemSpider	4984575 ;
UNII	N60H4ZDD14;
ChEMBL	ChEMBL95500 ;
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)	DTXSID80424381 ;
化学信息
化学式	C7H11NS
摩尔质量	141.23 g·mol−1
3D模型（JSmol（英语：JSmol））	交互式图像;
	SMILES CC(N)Cc1sccc1;
	InChI InChI=1S/C7H11NS/c1-6(8)5-7-3-2-4-9-7/h2-4,6H,5,8H2,1H3 ; Key:NYVQQTOGYLBBDQ-UHFFFAOYSA-N ;

1-(2-噻吩基)-2-丙胺，简称噻吩丙胺，是一种有机化合物，化学式为C₇H₁₁NS，它是一种兴奋剂。它可由2-(2-硝基-1-丙烯-1-基)噻吩经氢化铝锂还原^[3]，或1-(2-噻吩基)-2-丙酮和氨在钛酸四异丙酯催化下反应，经硼氢化钠还原得到^[4]。它和异硫氰酸甲酯反应，可以得到N-甲基-N'-[1-甲基-2-(2-噻吩基)乙基]硫脲。^[3]

参考文献

^ STATUS DECISION OF CONTROLLED AND NON-CONTROLLED SUBSTANCE(S) (pdf). Health Canada. 2013-07-31. [2025-02-28].
^ 国家禁毒办决定将尼秦类物质和12种新精神活性物质纳入管制. 人民网. 2025-06-19 [2025-06-19].
^ ^3.0 ^3.1 Foye, William O.; et al. Heterocyclic analogs of amphetamine: thioureas, dithiocarbamates, and negatively substituted amides. Journal of Pharmaceutical Sciences (1979), 68(5), 591-595.
^ Albarran-Velo, Jesus; et al. Markovnikov Wacker-Tsuji Oxidation of Allyl(hetero)arenes and Application in a One-Pot Photo-Metal-Biocatalytic Approach to Enantioenriched Amines and Alcohols. Advanced Synthesis & Catalysis (2021), 363(16), 4096-4108. doi:10.1002/adsc.202100351.

[1] STATUS DECISION OF CONTROLLED AND NON-CONTROLLED SUBSTANCE(S) (pdf). Health Canada. 2013-07-31. [2025-02-28].

[2] 国家禁毒办决定将尼秦类物质和12种新精神活性物质纳入管制. 人民网. 2025-06-19 [2025-06-19].

[Foye-3] 3.0 ^3.1 Foye, William O.; et al. Heterocyclic analogs of amphetamine: thioureas, dithiocarbamates, and negatively substituted amides. Journal of Pharmaceutical Sciences (1979), 68(5), 591-595.

[4] Albarran-Velo, Jesus; et al. Markovnikov Wacker-Tsuji Oxidation of Allyl(hetero)arenes and Application in a One-Pot Photo-Metal-Biocatalytic Approach to Enantioenriched Amines and Alcohols. Advanced Synthesis & Catalysis (2021), 363(16), 4096-4108. doi:10.1002/adsc.202100351.

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